The Roach lab is not in the phage-solutions business, we are in the phage-imagine business. This is where technology and imagination meet together and we create new therapeutic solutions.
Links to our work below.
Phage therapy in the resistance era: where do we stand and where are we going?
Tiffany Luong, Ann-Charlott Salabarria, Dwayne Roach
Clinical Therapeutics 2020
Standardized bacteriophage purification for personalized phage therapy.
Tiffany Luong, Ann-Charlott Salabarria, Robert Edwards, Dwayne Roach
Nature Protocols 2020
Stronger Together? Perspectives on phage-antibiotic synergy in clinical applications of phage therapy.
Anca Segall, Dwayne Roach, Stephanie Strathdee
Current Opinion in Microbiology 2019
Design of a broad-range bacteriophage cocktail that reduces Pseudomonas aeruginosa acute biofilms and treats infections in two animal models.
Francesca Forti, Dwayne Roach, Marco Cafora, Maria Pasini, David horner, Ersilia Fiscarelli, Martina Rossitto, Lisa Cariani, Federica Briani, Laurent Debarbieux, Daniela Ghisotti
Antimicrobial Agents & Chemotherapy 2018
Synergy between the host immune system and bacteriophage is essential for successful phage therapy against an acute respiratory pathogen.
Dwayne Roach, Chung Yin Leung, Marine Henry, Eric Morello, Devika Singh, James Di Santo, Joshua Weitz, Laurent Debarbieux
Cell Host & Microbe 2017
Phage therapy: awakening a sleeping giant.
Dwayne Roach, Laurent Debarbieux
Emerging Topics in Life Sciences 2017
Triple-acting lytic enzyme treatment of drug-resistant and intracellular Staphylococcus aureus.
Stephen Becker, Dwayne Roach, Vinita Chauhan, Yang Shen, Juli Foster-Frey, Anne Powell, Gary Bauchan, Richard Lease, Homan Mohammadi, William Harty, Chad Simmons, Mathias Schmelcher, Mary Camp, Shengli Dong, John Baker, Tamsin Sheen, Kelly Doran, David Pritchard, Raul Almeida, Daniel Nelson, Ian Marriott, Jean Lee, David Donovan
Scientific Reports 2016
Antimicrobial bacteriophage-derived proteins and therapeutic applications.
Dwayne Roach, David Donovan